RWE Data Scientist

Tit Job Title: Oncology Sr. RWE Data Scientist

Assignment Duration: 12+ Months (High possibility for long term extension)

Location: - Gaithersburg, MD

Location: Up to two days/week remote, minimum of three days onsite in Gaithersburg.

No traveling.

Key role within Global Technical Operations, focused on providing expert statistical and data analytical expertise.

This position emphasizes a strong foundation in biostatistics, with additional skills in data science and AI being highly desirable.

Working under the guidance of the Digital Transformation Lead, who oversees data, digital, and systems for Global Technical Operations, this role integrates biostatistics within the organization to deliver innovative solutions and support strategic business transformation in the biopharmaceutical industry.

Key Responsibilities:

The ideal candidate for this role will bring a proven track record of delivering value through the leverage of routinely collected data from healthcare settings to provide health analytics and insights in a range of contexts including Public Health, Pharmaceutical Research and Development and Commercial/ Payer.

They will collaborate with colleagues in Epidemiology, Statistics and Payer, giving scientific and technical guidance on study design, RW data selection and best practice in RW data utilization.

In addition, they will assist in advancing and shaping AZ’s Real World Science data strategy through the due diligence on new data providers/vendors, informatics support for data acquisitions in a range of Therapeutic Areas.

The role will promote best practice in Real World Data Science across multiple domains, and/or stakeholder groups.

Typical Accountabilities:
• Collaborate with Payer and Epidemiology teams to maximise the value derived from large

observational research data
• Deliver analyses of data from EMR, claims and primary observational data required by TA

RWE strategies
• Support the development of IVS strategies and selection of optimised contact models for prioritised markets through analysis of RWD
• Provide scientific guidance on the application of Real-World Evidence and observational research data to address issues across the Oncology and Biopharmaceuticals business units
• Provide technical input, options and directions to strategic decisions made by AZ observational study teams on study design, data partner selection and best practices in RWE data utilization
• Support technical teams to provide access to analytical tools and develop visual analytics to enable self-serving applications for end customers
• Provide clear technical input, options, and direction to strategic decisions on RWE platform and capability build
• Provide support for strategic decisions on AZ Medical Evidence and Observational Research external collaborations in the US and other markets
• Assist in building a capability that becomes a source of sustained competitive advantage for AZ in identifying, acquiring, integrating and mining diverse RW data from multiple geographic and healthcare system sources to support evidence generation and real-world studies
• Evaluate and assess strengths and weaknesses of external RW data sources, and potential partners for advancing the data strategy for specific therapeutic areas
• Maintain a strong insight into the capabilities of potential external partners in RWE, especially for US and emerging markets.

Education, Qualifications, Skills and Experience:

Essential:
• PhD or MS in data science or other advanced degree in life sciences with post-doctoral or other training/work in Medical/Health Informatics or related field.
• 5 years of experience
• Experience in real-world evidence and familiarity with health economics/epidemiology, and quantitative science such as health outcome modelling
• Expertise in EMR/Health IT, disease registries, and insurance claims databases
• Experience in Statistical Analysis Plan (SAP) generation and execution for observational studies
• Expertise in methods development and application using statistical languages such as R/Matlab/SAS/SQL/Hadoop/Python. R is strongly preffered, and SAS a plus.
• Experience in advanced visualisation and visual analytics of routinely collected healthcare

data

Desirable:
• Expertise in clinical data standards, medical terminologies and controlled vocabularies used in healthcare data and ontologies (ICD9/10/ReadCode)
• Experience in supporting pharmacoepidemiology studies with proven track record of advancing approaches with data science
• Expertise in data mining approaches within healthcare settings generating insight from routinely collected healthcare data
• A history of patient care or equivalent background of working at a patient care setting that allows the candidate to bring medical perspective into real-world evidence generation and observational studies
• Demonstrated ability to build long-term relationships with stakeholders at senior levels, understand relevant scientific/business challenges at a deep level and translate into a programme of informatics activities to deliver defined value
• Ability to lead & manage multi-disciplinary data science projects
• Strong track record of delivering large, cross functional projects
• Experience working in a global organization and delivering global solutions
• Use of Machine Learning and Artificial Intelligence in the generation of hypotheses within

Real World Data

HM pointed out the following is important to her:

• Direct work experience with data analysis, preferably in oncology area.

• Excellent technical skills and ability to pick up new tools quickly.

• Willing to learn.

• Exceptional communication skills, internally and externally. Commuicating and presenting to stakholders is key.